| Insert |
DNA: genomic Insert lengths(kb): 2.599999904632568 Gene product: homeo box B6(homeo box 2B, homologous to mouse Hox-2.2) [HOX2] Alleles: A1, A1, A1, A1, A1, A1, A2, A2, A2, A2, A2, A2 |
| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--5.6; SacI--3.7, 1.9; EcoRI/SacI--3.0, 1.9, 0.8; BamHI--5.6; HindIII--3.8, 0.95, 0.65. Contains an internal SacI site which cuts the insert into a 0.6 kb EcoRI/SacI fragment and a 2.0 kb SacI fragment. The BanII and SacII polymorphisms are the same system. Subcloned from lambda86x5B, mapping approximately 5 kb 5' of HOX2B. Enzyme(s) not detecting polymorphism: BamHI, BglII, BstEII, BstNI, DraI, EcoRV, HindIII, HincII, KpnI, PstI, PvuII, TaqI, XmnI (panel of 10-12 unrelated Caucasians). |
| References |
Murphy PD, et al. A moderately frequent RFLP identified by both SacI and BanII with a probe from the HOX2 locus in man (17q11-17q22). Nucleic Acids Res. 15: 6311, 1987. PubMed: 2888083
Kenneth K Kidd, personal communication
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